Beware of Beta
Founders, especially of startups with big ideas, tend to believe that they control their own destiny, which is a great mentality and probably a key prerequisite for being a successful founder. However, every company exists in a set of market and environmental conditions. Ideally, those conditions are such that companies can predominantly focus on their mission and execution (Alpha) and not be overly concerned with broader geopolitical, macroeconomic or financial market conditions (Beta). However, as any innovation investor who has been around a while knows, there can be periods (hopefully brief) when external conditions are so impactful that they must take precedence over the internal objectives, at least temporarily.
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